Phase II a Proof of concept study in Multiple Sclerosis (MS) patients with spasticity.
Single dose escalation followed by multiple fixed dose administrations to assess short term safety and to determine whether spasticity improves.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
160
The Neuroscience Research Centre, The Walton Centre NHS Foundation Trust
Liverpool, United Kingdom
The Royal London Hospital
London, United Kingdom
The National Hospital for Neurology and Neurosurgery
London, United Kingdom
Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust
Sheffield, United Kingdom
Numerical Rating Scale
Time frame: 26 days
Modified Ashworth Scale
Time frame: 26 days
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