ED Lung Protective Ventilation to Reduce Complications

Washington University School of Medicine1,705 enrolled

Overview

Early mechanical ventilation, if delivered with injurious settings, can lead to pulmonary complications, such as acute respiratory distress syndrome (ARDS). Mechanical ventilation in the emergency department (ED) has been studied infrequently when compared to the intensive care unit; however, data suggests that ED-based mechanical ventilation has significant room for improvement and may also be a causative factor in ARDS incidence.

This is a before-after study examining the impact of implementing lung protective ventilation in the emergency department.

Study Type

OBSERVATIONAL

Enrollment

1,705

Conditions

Mechanical Ventilation Ventilator-associated Conditions ARDS

Interventions

lung protective ventilationPROCEDURE

Lung protective ventilation strategy, which aims to deliver safe tidal volumes, appropriate PEEP, limit plateau pressure, and limit hyperoxia.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * mechanically ventilated via an endotracheal tube in the ED Exclusion Criteria: * death in the ED, * death or discontinuation of ventilation within 24 hours, * chronic mechanical ventilation, * ARDS while in the ED * transfer to another hospital.

Locations (1)

Washinton University School of Medicine in St. Louis

St Louis, Missouri, United States

Outcomes

Primary Outcomes

Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department

Time frame: 7 days

Secondary Outcomes

Number of Patients That Die During the Hospitalization

Time frame: Patients will be followed for the duration of hospital stay

Data from ClinicalTrials.gov

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