The primary aim of the current study was to investigate whether the consumption of vitamin D3 enriched, reduced-fat yellow cheese can counterbalance the expected decrease in serum 25-hydroxyvitamin D concentration during winter in postmenopausal women in Greece, and in what degree it can contribute as a potential food-based strategy for the prevention of vitamin D deficiency. A secondary aim was also to investigate any potential effect of the intervention in several quality of life (QoL) indices in the population of postmenopausal women under study.
Vitamin D status in postmenopausal women is of interest because of the association of low vitamin D status with increased risk of osteoporosis and related fractures. In addition, since there is increasing evidence that the dietary supply is often insufficient to offset the seasonal deficit in sunlight during winter months, fortified food and supplements are becoming important sources of dietary vitamin D intake to achieve optimal vitamin D status, especially in this high risk population. Although most studies have examined the effectiveness of vitamin D enriched milk and yogurt, there have been limited studies also exploring the effectiveness of vitamin D enriched cheese in enhancing vitamin D status and preventing vitamin D deficiency. However, fortification of cheese with vitamin D has certain technological considerations, particularly for reduced-fat varieties considering that vitamin D is a fat soluble nutrient. The primary aim of the current study was to investigate whether the consumption of vitamin D3 enriched, reduced-fat yellow cheese can counterbalance the expected decrease in serum 25-hydroxyvitamin D concentration during winter in postmenopausal women in Greece, and in what degree it can contribute as a potential food-based strategy for the prevention of vitamin D deficiency. A secondary aim was also to investigate any potential effect of the intervention in several quality of life (QoL) indices in the population of postmenopausal women under study. .
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
80
60 grams of vitamin D3 enriched, reduced-fat yellow cheese provide 5.7 micrograms of vitamin D per day for 8 weeks
60 grams of plain (non-fortified), reduced-fat yellow cheese provide 0 micrograms of vitamin D per day for 8 weeks
Harokopio University of Athens
Kallithea, Attica, Greece
serum 25-hydroxyvitamin D concentration
Time frame: 8 weeks
physical functioning scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to physical functioning\] to 100 \[no disability related to physical functioning\]
Time frame: 8 weeks
role limitations due to physical health scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to limitations due to physical health\] to 100 \[no disability related to limitations due to physical health\]
Time frame: 8 weeks
role limitations due to emotional problems scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to limitations due to emotional problems\] to 100 \[no disability related to limitations due to emotional problems\]
Time frame: 8 weeks
vitality scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to vitality to 100 \[no disability related to vitality\]
Time frame: 8 weeks
emotional well-being scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to emotional well-being to 100 \[no disability related to emotional well-being\]
Time frame: 8 weeks
social functioning scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to social functioning to 100 \[no disability related to social functioning\]
Time frame: 8 weeks
bodily pain scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst disability related to bodily pain\] to 100 \[no disability related to bodily pain\]
Time frame: 8 weeks
general health scale, Short Form 36 health survey questionnaire (SF-36)
score range from 0 \[worst general health\] to 100 \[best general health\]
Time frame: 8 weeks
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