Postoperative Analgesic Effects of Using Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block

TC Erciyes University93 enrolled

Overview

we aimed postoperative analgesic effects of using bupivacaine alone or added dexmedetomidine for ultrasound guided thoracic paravertebral block in thoracotomy

paravertebral block is commonly used in the treatment for acute and chronic pain.The duration of paravertebral block could theoretically be prolonged with neurolytic agents. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Pain

Interventions

bupivacaineDRUG

21 ml 0.5 %bupivacaine is applied paravertebral space

dexmedetomidinDRUG

1 ml dexmedetomidin + 20 ml 0.5 % bupivacaine are applied paravertebral space

serum physiologicDRUG

21 ml serum physiologic is applied paravertebral space

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA 1-2 * 18-65 aged * patient undergoing thoracotomy Exclusion Criteria: * chronic opioid consumption * bupivacaine and dexmedetomidine allergies * coagulopathy * infection at the needle insertion side * chronic liver and kidney disease

Locations (1)

Erciyes University Medicine Faculty

Kayseri, Turkey (Türkiye)

Outcomes

Primary Outcomes

opioid consumption

patient controlled analgesia

Time frame: postoperative 24 hours

Secondary Outcomes

visual analog scale

Time frame: postoperative 1 day

Data from ClinicalTrials.gov

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