Efficiency of Piezo-Corticision in Accelerating Orthodontic Tooth Movement

Study Subjects for Part I and Part II: Inclusion: * Voluntary participation of patients only * Able to follow instruction, able to understand the consent form and sign it. * Adult Female and Male Saudi patients 15-35 y.o * Subjects who are none smokers * Subjects with good health according to American Society of Anesthesiology ASA-I with full permanent dentition regardless of the third molars. * Subjects with good periodontal and gingival health: Gingival Index GI≤ 1 * Subjects with a none gummy smile, * Subjects with full complement of permanent caries-free dentition; Restored teeth should be of proper sound intact fillings * Subjects without root anomalies * Subjects with mild-moderate skeletal and dental cephalometric measurements: OB ≤ 40%, OJ ≤ 6, ANB ≤ 5 °, SN-GOGN ≤ 29 °, Subjects' dentition Angle classification class II div 1, 3mm molar and canine occlussal relationship; and subjects with class 1 Bi-maxillary protrusion Exclusion: * Subjects younger than 15 y.o * Subjects who cannot comprehend the surgical procedure and who cannot consent for themselves * Subjects who are medically classified as ASA-II, III * Subjects who are taking any systemic or local medications especially Insulin, non-steroidal anti-inflammatory drugs, bisphosphonate, corticosteroids * Subjects who are pregnant * Subjects who are smokers * Subjects with craniofacial syndromes: cleft lip and palate; or facial trauma * Subjects with unhealthy or compromised periodontium * Subjects with a gummy smile * Subjects with inadequately treated endodontic and dental fillings problems * Subjects with previous root resorption or dental developmental anomalies * Subjects who had previous orthodontic treatment * Subjects with TMJ signs and symptoms; Mandibular functional shift * Subjects with extreme skeletal and dental class II: SN-GOGN ≥ 32°, OJ ≥ 6mm * Subjects will be excluded if broken brackets or lost coils which have not been replaced immediately within few days from breakage or loss. * Subjects will be excluded if any of mini-screws failed during treatment * Subjects who become medically unfit during course of trial