Emdogain Minimally Invasive Surgical Technique

Inclusion Criteria: * Subjects must have voluntarily signed the informed consent form before any study related procedures * Subjects must be males or females who are 18-85 years of age * Subjects must have moderate to severe chronic, generalized periodontitis with pockets of 5 mm - 8mm probing depth in at least 2 pockets per contralateral quadrants in one arch (study teeth) * Subjects must be committed to the study and the required follow-up visits * Subjects must be in good general health as assessed by the Investigator Exclusion Criteria: * Subjects taking or intending to take any medications during the duration of the study that will potentially affect healing and inflammation * Subjects who are currently heavy smokers (defined \>10 cigarettes per day or \>1 cigar per day) or who use chewing tobacco * Subjects being treated with systemic antibiotics or subjects that were treated with systemic antibiotics within 3 months prior to treatment in this study * Subjects with uncontrolled diabetes * Subjects that are immunocompromised or immunosuppressed * Subjects that cannot provide informed consent * Subjects with drug or alcohol abuse * Subjects that have undergone periodontal root planing or periodontal surgery in the last 6 months * Subjects that are pregnant * Subjects with necrotizing periodontitis or periodontitis related to systemic disease * Teeth with pockets with probing depth ≥ 9 mm will not classify as study teeth * Teeth with pockets or defects with furcation involvement will not classify as study teeth * Teeth with mobility degree \> 1 without splint will not classify as study teeth * Subjects with test and control sites in the two quadrants on adjacent teeth * Patients with compromised health conditions such as diabetes, systemic diseases, high dose steroid therapy, bone metabolic diseases, radiation or immune-oppressive therapy, and infections or vascular impairment at the surgical site * Subjects with conditions or circumstances, in the opinion of the Investigator , which would prevent completion of study participation or interfere with analysis of study results