Patients with gallstone and confirmed common bile duct stones are registered in this study. The three managements for common bile duct stones are endoscopic sphincterotomy (EST), laparoscopic common bile duct exploration (LCBDE) and laparoscopic transcystic common bile duct exploration (LTCBDE). Patients will be assessed at baseline, preoperative investigations, operative method, operative time, conversion to open procedure, intraoperative and postoperative complications, and the presence of retained and recurrent stones. All patients were followed up for 3 years by telephone interview ang outpatient visits. Abdominal US and liver function tests were carried out whenever any abdominal symptom appeared during the follow-up period. If there were unusual findings, magnetic resonance cholangiopancreatography(MRCP) was carried out.
Study Type
OBSERVATIONAL
Enrollment
2,700
Sphincterotomy (EST) is performed to remove the common bile duct stone.
Transductal exploration was carried out to remove the common bile duct stone. Primary closure or a T tube drainage was performed according to the results of transductal surgery.
A wide local dissection of Calot's triangle is performed and a 2.8mm, 3-mm or 5-mm flexible choledochoscope according to the diameter of the cystic duct is inserted through the cystic duct into the common bile duct. After the common bile duct stone is removed, the cystic duct was ligated with Hem-o-lok.
Laparoscopic cholecystectomy is performed to remove the gallbladder.
Beijing Friendship Hospital
Beijing, Beijing Municipality, China
Rate of Adverse outcomes
The patients with complication / the total patients
Time frame: 3 years
Incremental cost-effectiveness ratio
the average incremental cost associated with 1 additional unit of the measure of effect
Time frame: 3 years
Hospital stay
The total days in hospital
Time frame: 3 years
Acute cholangitis rate
The patients with acute cholangitis / the total patients
Time frame: 30 days
Bile leakage rate
The patients with bile juice found in the abdominal cavity after procedures / the total patients
Time frame: 30 days
Stricture of the bile duct rate rate
The patients with any stricture appeared after the procedures / the total patients
Time frame: 3 years
Mortality
Number of death connected with the procedures and complications / total patients
Time frame: 3 years
Perforation Rate
The patients with perforation after the procedures / the total patients
Time frame: 30 days
Hemorrhage Rate
The patients with hemorrhage after the procedures / the total patients
Time frame: 3 years
Operation time
The total time of all the procedures (min)
Time frame: 3 years
Acute pancreatitis Rate
The patients with acute pancreatitis after the procedures / the total patients
Time frame: 30 days
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