Transcriptomics Signature of Anti Vaccinia Memory B Cells

Institut National de la Santé Et de la Recherche Médicale, France4 enrolled

Overview

Analyse the transcriptomic signature of anti vaccinia memory B cells at a short time after vaccination as compared to the signature already established in long-lived memory B cells.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Healthy

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy donors vaccinated against smallpox Exclusion Criteria: * none

Locations (1)

Institut Necker Enfants Malades U1151, Faculté de Médecine-Paris Descartes, site Broussais, Bâtiment Leriche, porte 9, CS 61431, 14 Rue Maria Helena V

Paris, France

Outcomes

Primary Outcomes

Analysis of B memory cells

B-memory cells will be analysed to determine, on an individual basis, whether they express the long-lived signature

Time frame: 12 months

Data from ClinicalTrials.gov

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