Malignant Genito-urinary Tumors in Children: South Egypt Cancer Institute Experience

Assiut University250 enrolled

Overview

The aim of this study is to identify demographic \& disease characteristics in pediatric oncology patients diagnosed with one of genitourinary tumors \& treatment outcomes in these patients.

Background: Tumors of the kidney, bladder, prostate, testis, and adrenal represent a large part of the adult urologic practice, but are relatively infrequent in children. Genitourinary tumors contribute to pediatric solid tumors. Wilms tumor, rhabdomyosarcoma, and germ cell tumors are the most common malignant genitourinary tumors in children. The natural history and management of these tumors in the pediatric age is different from that of the adults. As result of the successful work of several clinical trial groups in recent decades, there has been a significant improvement in their cure rates. Patients \& Methods: From January 2001 till December 2015, retrieval \& analysis of the medical records of pediatric patients with genitourinary tumors will be made at the pediatric oncology department, South Egypt Cancer Institute which represents the largest referral center in Upper Egypt. These data will be categorized according to demographic characteristics, clinico-pathologic features, treatment modalities received, and outcomes of treatments in these patients.

Study Type

OBSERVATIONAL

Enrollment

250

Conditions

Genitourinary Neoplasms Neoplasms, Genitourinary

Eligibility

Sex: ALLMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients whose age less than or equal to 18 years. * Patients diagnosed with any of neoplasms affecting the genitourinary system. Exclusion Criteria: * Patients whose age more than 18 years.

Locations (1)

Assiut University

Asyut, Egypt

RECRUITING

Outcomes

Primary Outcomes

Overall survival (OS)

Time from the date of initiation of treatment until death from any cause

Time frame: Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years

Event Free Survival (EFS)

Time from the date of initiation of treatment until disease progression, or death for any reason.

Time frame: Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years

Data from ClinicalTrials.gov

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