PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding

Inclusion Criteria All subjects accepted for this study must: * Be 18 years of age * Be undergoing elective cardiac surgical procedure utilizing cardiopulmonary bypass * Have evidence of excessive microvascular bleeding in the surgical field as determined by the surgical team in addition to a PT \>16.6 sec or INR \>1.6 sec. Exclusion Criteria Subjects who have one or more of the following will be excluded from the study: * Are unable to grant informed consent or comply with study procedure * History of hypercoagulable condition (e.g. Factor V Leiden, AT-3 deficiency, Prothrombin gene mutation, Anti-phospholipid antibody syndrome, etc) or previous unprovoked thromboembolic complications * Coagulopathic conditions such as factor deficiencies, factor inhibitors, heparin induced thrombocytopenia, or use of intravenous anticoagulants other than heparin at the time of cardiovascular surgery * Thromboembolic event within past 3 months * Received oral therapy with clopidogrel, prasugrel, rivaroxaban or dabigatran within the past 5 days * Patients taking chronic warfarin therapy who have not discontinued treatment and demonstrated an INR \<1.3 prior to surgery * Fibrinogen level \<150 mg/dL on initial post cardiopulmonary bypass labs * Antithrombin 3 level \< 80% control (preoperative) * Are undergoing emergency open heart-surgery * Cardiopulmonary bypass time is expected to be \< 30 minutes * Age \< 18 years of age * Are pregnant