Effects of Pomegranate Juice on Oxidative Stress in Patients With type2 Diabetes

National Nutrition and Food Technology Institute60 enrolled

Overview

Introduction: Diabetes mellitus a chronic diseases, is the most common and important metabolic disease in human. Increased free radicals production due to hyperglycemia produces oxidative stress which worsens the disease and its complications. Pomegranate juice has antioxidant and antiatherosclerotic properties. The present study was planned to evaluate the effects of pomegranate juice consumption on glycemic control, lipid profile,blood pressure and oxidative stress in patients with type 2 diabetes

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Diabetes Type 2

Interventions

pomegranate juiceDIETARY_SUPPLEMENT

lifestyle modificationBEHAVIORAL

Eligibility

Sex: ALLMin age: 40 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age of 40-65 years * Body Mass Index 18.5-30 * Fasting blood glucose ≥ 126 mg/dl Exclusion Criteria: * Smoking * insulin for blood glucose control * taking estrogen or progesterone (if female) * Taking antioxidant supplements * suffering from any other chronic diseases * Participants are also excluded if they missed more than 10% of their pomegranate juice packs

Locations (1)

NNFTRI clinic

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

total antioxidant capacity

Time frame: 6 weeks

Secondary Outcomes

fasting blood glucose

Time frame: 6 weeks

Data from ClinicalTrials.gov

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