The purpose of this study is to conduct a pilot trial investigating cognitive training in older Veterans with a history of traumatic brain injury (TBI) to assess training effects, acceptability of training to participants, and to explore whether other factors influence training effects.
A study of older Veterans (60-85 years old) who have 1) a history of repetitive mild TBI or at least one moderate TBI and 2) subjective cognitive complaints. Participants will be randomized to one of three conditions for 4 weeks: Project:Evolution (EVO) multitask video game, EVO words video game, or an assessment only control condition. Participants will complete assessment visits at baseline, post-intervention (1 month after baseline), and 3 months post-intervention (4 months after baseline).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
SINGLE
Enrollment
89
Participants will play a multitasking game for 4 weeks
Participants will play a word puzzle game for 4 weeks
San Francisco VA Medical Center
San Francisco, California, United States
Veterans Home of California
Yountville, California, United States
Acceptability based on participant ratings
Time frame: Acceptability ratings assessed post-intervention (1-month after baseline)
Participant adherence to game play
Time frame: Total adherence over the 4 week intervention phase
Change in cognitive functioning based on neurocognitive test battery
Time frame: Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline)
Change in self-reported everyday cognitive functioning [Neuro-QOL (Quality of Life in Neurological Disorders) Cognitive Function inventory]
Time frame: Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline)
Change in everyday functioning [University of California San Diego (UCSD) Performance Based Skills Assessment (UPSA)]
Time frame: Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline)
Change in mood symptoms (Geriatric Depression Scale)
Time frame: Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline)
Change in EVO performance (EVO Monitor)
Time frame: Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline)
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