Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Skin Prick Test Positive Control

Mahidol University180 enrolled

Overview

Skin prick test (SPT) was used for diagnostic test for type 1 hypersensitivity. The efficacy and safety of SPT were proved. The positive control of SPT is histamine. In Thailand, the most common concentration of histamine for SPT is 10 mg/ml. However, in some practice they use other concentration (1, 2.5 mg/ml). This study will find the proper concentration of histamine for positive control use in SPT.

Appropriate concentration of histamine positive control is important in interpretation the result of skin prick test.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

180

Conditions

Immediate Hypersensitivity

Interventions

SPTPROCEDURE

SPT of histamine concentration 1, 5 and 10 mg/ml

Eligibility

Sex: ALLMin age: 7 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Parcitipate person who attented allergy clinic, ENT clinic * Legible in Thai language Exclusion Criteria: * Patient cannot withhold antihistamine drug * Pragnancy and lactation mother * comorbid disease such as cardiac disease, liver, renal, hypertension and severe asthma

Locations (1)

Faculty of Medicine Siriraj Hospital

Bangkoknoi, Bangkok, Thailand

Outcomes

Primary Outcomes

Mean wheal diameters of SPT of different histamine concentrations.

compare mean wheal diameters of histamine concentration 1,5, and 10 mg/ml

Time frame: 1 years

Secondary Outcomes

Mean wheal diameters of SPT of local and imported histamine positive concentration

compare mean wheal diameters of imported histamine 1 mg/ml to local histamine

Time frame: 1 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.