The purpose of the study is to develop methods to identify predictors of Malignant Hyperthermia.
The current study will use the combination of electronic medical records and genomic information in samples of persons who have exhibited signs of Malignant Hyperthermia (MH) or have family history or high risk of MH to see if risk factors can be identified. These will be compared with control samples of children who have been exposed to the same agents which could induce MH, yet showed no signs of the disorder.
Study Type
OBSERVATIONAL
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Number of clinical manifestations of malignant hyperthermia
Incidence of clinical manifestations of MH will be compared among patients with a history of MH to controls (no diagnosis of MH).
Time frame: Within data collection period (3 years total).
number of Genetic indications for malignant hyperthermia
genetic indications for malignant hyperthermia will be compared between control subjects and subjects with a diagnosis of MH
Time frame: Within data collection period (3 years total).
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