Effect of BM-MSCs in DCD Kidney Transplantation

Inclusion Criteria: 1. Primary kidney transplantation 2. Receiving induction therapy and combined immunosuppressive regimens (CNIs + MPA + steroids) 3. Patient is willing and capable of giving written informed consent for study participation and able to participate in the study for 12 months Exclusion Criteria: 1. Secondary kidney transplantation 2. Combined or multi-organ transplantation 3. Women who are pregnant, intend to become pregnant in the next 1 years, breastfeeding, or have a positive pregnancy test on enrollment or prior to study medication administration 4. Panel reactive antibody (PRA)\>20% 5. CDC crossmatch is positive 6. Donors or recipients are known hepatitis C antibody-positive or polymerase chain reaction (PCR) positive for hepatitis C 7. Donors or recipients are known hepatitis B surface antigen-positive or PCR positive for hepatitis B 8. Donors or recipients are known human immunodeficiency virus (HIV) infection 9. Patients with active infection 10. Recipients with a history of substance abuse (drugs or alcohol) within the past 6 months, or psychotic disorders that are not capable with adequate study follow-up. 11. Patients with severe cardiovascular dysfunction 12. WBC\<3\*10\^9/L or RBC \<5g/dL 13. Highly allergic constitution or having severe history of allergies. 14. Patients with active peptic ulcer disease, chronic diarrhea, or gastrointestinal problem affect absorption 15. Patients with a history of cancer within the last 5 years 16. Prisoner or patients compulsorily detained (involuntarily incarcerated) for treatment or either a psychiatric or physical (e.g. infectious disease) illness