Airway Resistance Measurement in Children 3 to 6 Years of Age

University Hospital, Brest130 enrolled

Overview

In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw). Even if Rint is easily and routinely performed, it also includes a component of lung tissue and chest wall resistance as well as respiratory tissue viscoelasticity. sRaw seems to be better for discriminating airway obstruction. These two techniques will be compared in terms of concordance in the diagnosis of pulmonary obstruction and bronchodilator response.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

130

Conditions

Airway Obstruction

Interventions

airway resistance measurementOTHER

assessment of airway resistance

Eligibility

Sex: ALLMin age: 3 YearsMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Child 3 to 6 years aged Exclusion Criteria: * Height below 90 centimeters * Opposition to participation

Locations (1)

CHRU de Brest

Brest, France

Outcomes

Primary Outcomes

airway resistance measure by interruption technique (Rint)

Rint is performed using Spiroteq Dyn'R during a 100 ms occlusion and calculated using the linear back extrapolation method

Time frame: Day one

Secondary Outcomes

measure of bronchodilator response

Bronchodilator response is assessed with Rint and sRaw measurement

Time frame: Day one

Data from ClinicalTrials.gov

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