Prognosis of Bronchiectasis in Children--A Multicenter Prospective Cohort Study

Baoping XU300 enrolled

Overview

This prospective cohort study is designed to observe of the effect of intervention therapy on the long-term prognosis of children with bronchiectasis. The main purpose of the study was to evaluate the degree of deterioration of lung function, to observe and compare the quality of life, the time of pulmonary exacerbation, and the changes of lung image.

All enrolled patients are followed up for half a year, 1 years, 2 years, 3 years, 4 years, 5 years, while observation of pulmonary function, symptoms, signs, quality of life, the times of acute pulmonary exacerbation, and the changes of lung image are performed.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Bronchiectasis

Eligibility

Sex: ALLMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria:A included patient must be coincident at least one point of the four items of high-resolution computed tomography (HRCT) manifestations. * Internal bronchial diameter greater than the accompanying pulmonary artery. * lack of bronchial tapering * bronchi visible in the peripheral 1cm of lung * bronchial diameter greater than adjacent segmental bronchi Exclusion Criteria:Subject will be excluded if she or he has one of the following * It is unable or doesn't agree to accept the follow-up process * undergoing trial for other medications or instruments.

Locations (1)

Beijing Children'S Hospital

Beijing, Beijing Municipality, China

RECRUITING

Outcomes

Primary Outcomes

Change from baseline in lung function on the spirometry

forced expiratory volume at one second (FEV1) in Liter

Time frame: 5 years

Central Contacts

Baoping Xu, MD,PhD

CONTACT

861059616308 xubaopingbch@163.com

Data from ClinicalTrials.gov

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