Olfaction Disorders in Patients Included in The Trauma Brain Injury (TBI) Database at Trondheim University Hospital

St. Olavs Hospital20 enrolled

Overview

The aim of the study is to see whether patients with chronic smell impairment after brain injury benefit from a treatment that consists of corticosteroids, and then olfactory training in 3 months.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Brain Injuries Olfaction Disorders

Interventions

corticosteroidsDRUG

olfactory stimulationBEHAVIORAL

stimulation with odorants by sniffing 4 different odorants for a total of 5 minutes twice a day during 3 months

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Registered in the TBI Database * 18-65 years of age per 01.10. 2012 * Olfaction score by Sniffin Sticks Threshold-Discrimination-Identification (TDI) \< 30 confirming dysosmia Exclusion Criteria: * Unable to express senses. * Unable to follow treatment and protocol * pregnancy * diabetes * tendency to infections * hypertonia * dyspepsia * interfering medication (hormonal treatment, NSAIDS, antidiabetics, barbiturates, fenitoin, carbamazepin, rifampicin, cyclophosphamides)

Locations (1)

ENT department St Olavs Hospital

Trondheim, Norway

Outcomes

Primary Outcomes

number of patients who have improved olfaction perception (by at least 5 points on the Threshold-Discrimination-Identification (TDI) score

TDI score measured by Sniffin Sticks

Time frame: 1 year

Data from ClinicalTrials.gov

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