An Open-label, Long-term, Safety Study of Lasmiditan for the Acute Treatment of Migraine

Inclusion Criteria: * Able and willing to give written informed consent and authorize Health Insurance Portability and Accountability Act (HIPAA). * Completed COL MIG-301 or COL MIG-302 within the last 12 weeks. Subjects that completed COL MIG-301 prior to COL MIG-305 being available will be allowed to enroll as long as enrollment occurs within 4 weeks of COL MIG-305 activation at their site. (NOTE: Additional subjects may qualify if they completed COL MIG-301 or COL MIG-302 \>12 weeks prior or if they have not participated in either prior study, but meet eligibility criteria outlined for COL MIG-302.) * Females of child-bearing potential must be using or willing to use a highly effective form of contraception (e.g. combined oral contraceptive, intrauterine device (IUD), abstinence or vasectomized partner). * Able and willing to complete an electronic diary to record details of all migraine attacks treated with study drug. Exclusion Criteria: * Any medical condition or clinical laboratory test which in the judgment of the Investigator makes the subject unsuitable for the study. * Pregnant or breast-feeding women. * Women of child-bearing potential not using or not willing to use highly effective contraception. * Participant is at imminent risk of suicide (positive response to question 4 or 5 on the Columbia Suicide Severity Rating Scale (C-SSRS). * Initiation of or a change in concomitant medication to reduce the frequency of migraine episodes since completing COL MIG-301/LAHJ (NCT02439320) or COL MIG-302/LAHK (NCT02605174). * Participation in any clinical trial of an experimental drug or device since completing EoS/Visit 2 of COL MIG 301/LAHJ (NCT02439320) or COL MIG-302/LAHK (NCT02605174).