The purpose of this prospective randomized controlled study is to compare the improvement of symptoms from benign prostatic hyperplasia (BPH) and the improvement of QoL, in patients undergoing prostatic artery embolization (PAE) or conventional transurethral resection of the prostate (TURP).
The purpose of this prospective randomized controlled study is to compare the improvement of symptoms from benign prostatic hyperplasia (BPH) as assessed by the International Prostate Symptom Score (IPSS) and the improvement of QoL assessed by QoL questionnaire in patients undergoing prostatic artery embolization (PAE) to patients of similar characteristics undergoing conventional transurethral resection of the prostate (TURP).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Embolization of the prostate with gelatin embolization spheres via microcatheterization of the prostatic arteries.
Gelatin embolization microspheres (300-500 microns) will be used as embolic material for the prostatic artery embolization (PAE) protocol
Bipolar transurethral resection of the prostate
Hospital Universitario Lozano Blesa
Zaragoza, Spain
Improvement of symptoms
Improvement (change) of symptoms assessed by IPSS Score (International Prostate Symptom Score )
Time frame: 12 months
Improvement in QoL
Improvement (change) of quality of life assessed by QoL score
Time frame: 12 months
Duration of hospitalization post procedure
Number of days of postprocedure hospitalization
Time frame: 3 weeks
Preservation of erectile function
Change from baseline in erectile function using the International Index of Erectile Function (IIEF)
Time frame: 12 months
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A bipolar electrosurgery generator will be used to perform transurethral resection of the prostate (TURP)