A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects

Inclusion Criteria: * Subject is a female of non-childbearing potential or male, who is healthy, nonsmoking, and 18 to 60 years old, inclusive, at screening * Male subjects agree to use contraception * Willing and able to give written informed consent Exclusion Criteria: * Evidence or history of clinically significant metabolic, allergic, dermatological, hepatic, renal,hematological, pulmonary, cardiovascular, gastrointestinal, neurological, or psychiatric disorder * History of hypersensitivity or allergy to drugs, foods, or other substances * History or presence of abnormal electrocardiogram or hypertension * History of alcohol abuse, illicit drug use, significant mental illness, physical dependence to any opioid, or any history of drug abuse or addiction within 1 year of screening * Participated in another clinical trial of an investigational drug within 30 days (or 5 half-lives of the investigational drug, whichever is longer) prior to Screening