Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy

Inclusion Criteria: * Males and Females * 18 to 65 years of age * Baseline LDL-C ≥ 130 mg/dL (3.4 mmol/L) Exclusion Criteria: * If female, postmenopausal or surgically menopausal * Triglycerides (TG) \>400 mg/dL * Creatine phosphokinase (CPK) \>3 × the upper limit of normal (ULN) * Body Mass Index (BMI) \>35 kg/m2 * Uncontrolled diabetes mellitus (HbA1c \>10%) * Renal dysfunction (blood urea nitrogen \[BUN\] or creatinine \>2 × ULN) * Hepatic dysfunction (aspartate aminotransferase \[AST\] or alanine aminotransferase \[ALT\] \>2 × ULN) * Myocardial infarction, severe or unstable angina pectoris, coronary angioplasty, coronary artery bypass graft, or any other major cardiovascular event resulting in hospitalization in previous month