Omics4Aging: Stratification of Frailty Population

Inclusion Criteria: Unless otherwise specified, subjects who fulfill all of the following will be included: 1. Caucasian 2. Male or female between the ages of 65 and 79 years old 3. Three or more Fried Frailty Criteria (as diagnosed by investigator) 4. Informed consent obtained Exclusion Criteria: Any of the following criteria would render a subject ineligible for inclusion: 1. Dementia (previously diagnosed by general practitioner) 2. Hb1c (glycate Haemoglobin) \>7.5% (\>58 mmol/mol). 3. End stage disease (1 year after last chemotherapy treatment for cancer) 4. Drug abuse (alcohol - assessed by investigator) 5. Medications: no antibiotic treatment (for at least 4 weeks), immune suppressants, and or chronic use of corticosteroids 6. Currently participating or having participated in another clinical or nutritional intervention trial during the last 3 month 7. Chronic active inflammatory disease (e.g. rheumatoid arthritis, vasculitis, lupus erythematosus and Crohn's disease) 8. Chronic Active hepatitis 9. Kidney failure in Dialysis treatment 10. Any other condition that in the judgment of the lead investigator would not allow the subject to complete the study protocol