The purpose of this study is to evaluate the splenic activation in hypertensive patients, as compared to normotensives, using FDG-PET/CT imaging. Moreover, the investigators will investigate whether the splenic metabolic activity relates to the expression of circulating inflammatory proteins (high-sensitivity C-reactive protein \[hsCRP\]), interleukin-1b (IL-1b), tumor necrosis factor-a (TNF-a) or to immune profiles of activated T cells.
Study Type
OBSERVATIONAL
Enrollment
120
PET/CT scan
IRCCS Neuromed
Pozzilli, (IS), Italy
RECRUITINGSplenic metabolic activity
18FDG uptake in splenic tissue
Time frame: At enrollment
Circulating pro-inflammatory markers
Serum levels of pro-inflammatory cytokines
Time frame: At enrollment
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