This prospective cohort study aims to determine the incidence of hospitalization-associated disability and its association with risk factors at the patient level and with care and hospital processes. For this, patients aged 70 years or older admitted for elective valve surgery or elective transcatheter aortic valve implantation or as a result of symptomatic moderate to severe valvular heart disease will be consecutively included from 01 October 2015 to 29 February 2016.
Study Type
OBSERVATIONAL
Enrollment
80
Universitaire Ziekenhuizen Leuven
Leuven, Vlaams-Brabant, Belgium
Hospitalization-associated Disability
The loss of ability to complete one of the basic ADLs independently between baseline and hospital discharge.
Time frame: Up to 30 days post-hospital discharge
The six minutes walking distance test
Time frame: Up to 30 days post-hospital discharge
Five meter gait speed test
Time frame: Up to 30 days post-hospital discharge
Timed get-up and go test
Time frame: Up to 30 days post-hospital discharge
Peak extension torque measured at the right side and evaluated at 60° of knee flexion
Isometric quadriceps strength will be measured using a dynamometer (Biodex system 4 pro; Enraf Nonius; Delft, The Netherlands)
Time frame: Up to 30 days post-hospital discharge
Peak handgrip force assessed at the dominant side with the elbow at 90° of flexion, and the forearm and wrist in a neutral position.
Isometric handgrip force will be measured with a hydraulic hand dynamometer (Jamar dynamometer; JA Preston Corporation; Jackson, MI)
Time frame: Up to 30 days post-hospital discharge
Inappropriate medication prescribing
Inappropriate medication prescribing using the RASP-list (Rationalization of Home Medication by an Adjusted STOPP list in Older Patients)
Time frame: Up to 30 days post-hospital discharge
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