Safety, Tolerability, and Immunogenicity of V114 Compared to Prevnar 13™ in PPSV23-vaccinated Healthy Adults ≥65 Years of Age (V114-007)

Inclusion Criteria: * Is in good health (any underlying chronic illness must be documented to be in stable condition) * Has documented proof of receipt of 23-valent pneumococcal polysaccharide vaccine ≥1 year prior to study entry * Is a male or postmenopausal female Exclusion Criteria: * Has received prior administration of any pneumococcal vaccine other than 23-valent pneumococcal polysaccharide vaccine * Has a history of invasive pneumococcal disease or known history of other culture-positive pneumococcal disease * Has a known hypersensitivity to any component of the pneumococcal conjugate vaccine, or any diphtheria toxoid-containing vaccine * Is known or suspected impairment of immune function * Has received systemic corticosteroids for \>=14 consecutive days and has not completed treatment \<=30 days prior to study entry, or received systemic corticosteroids exceeding physiologic replacement doses within 14 days prior to study vaccination * Has a coagulation disorder contraindicating intramuscular vaccination * Receives immunosuppressive therapy, including chemotherapeutic agents used to treat cancer or other conditions, and treatments associated with organ or bone marrow transplantation, or autoimmune disease * Has received a blood transfusion or blood products, including immunoglobulins within the 6 months before receipt of study vaccine or is scheduled to receive a blood transfusion or blood product within 30 days of receipt of study vaccine. Autologous blood transfusions are not considered an exclusion criterion * Has participated in another clinical study of an investigational product within 2 months before the beginning of or any time during the duration of the current clinical study * Is a user of recreational or illicit drugs or has had a recent history (within the last year) of drug or alcohol abuse or dependence.