Intraoperative Sedation and Postoperative Delirium

Seoul National University Bundang Hospital855 enrolled

Overview

Delirium are common after orthopedic surgery in the elderly and are directly associated with loss of independence, reduction in the quality of life and increased mortality. The cause of postoperative delirium still remains unclear and may be multifactorial. The aim of this retrospective study is to examine prevalence of postoperative delirium according to the use of dexmedetomidine or propofol in elderly patients undergoing orthopedic surgery under regional anesthesia.

Study Type

OBSERVATIONAL

Enrollment

855

Conditions

Orthopedics

Interventions

DexmedetomidineDRUG

PropofolDRUG

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who underwent orthopedic surgery under regional anesthesia * age of 65 years or greater Exclusion Criteria: * General anesthesia * age \< 65 years * central nervous system disease, including dementia and Parkinson's disease * Patients who were not received sedation with propofol or dexmedetomidine during the operation

Locations (1)

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea

Outcomes

Primary Outcomes

delirium

Time frame: within 7 day postoperatively

Secondary Outcomes

Wound infection

Time frame: within 7 day postoperatively

Pulmonary thromboembolism

Time frame: within 7 day postoperatively

Hospital stay

Time frame: through study completion, an average of 7days

Data from ClinicalTrials.gov

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