There are conflicting results in earlier studies concerning the safety and efficacy of epidural oxycodone. In a study by Bäcklund and colleagues, epidural oxycodone was as effective as intravenous oxycodone, so they did not recommend epidural use of oxycodone. In another study, Yanagidate and Dohi reported that oxycodone was as effective in pain treatment with double dose compared to epidural morphine. In our previous study, epidural oxycodone provided safe and effective pain relief when compared to intravenous oxycodone. In the present study, the aim was to compare the efficacy and safety of epidural or intravenous oxycodone in patients undergoing elective gynecological surgery with planned epidural pain treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
100
Oxycodone intravenously 0,1mg/kg
Oxycodone 0,1 mg epidurally
Kuopio University Hospital
Kuopio, Northern Savonia, Finland
amount of rescue medicine
The amount of rescue pain medication given after study drug administration up to four hours
Time frame: from zero hours up to four hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.