The aim of this case control study is to explore the possible association between periodontal destruction and serum anti-CCP antibodies in RA patients and healthy subjects.
In patients with RA, the anti-CCP antibody titer seems positively correlated to their periodontal destruction and disease activity in comparison with healthy subjects.
Study Type
OBSERVATIONAL
Enrollment
47
National Taiwan University Hospital
Taipei, Taiwan
Serum level of anti-cyclic citrullinated peptide/protein antibody
Lower then 7 Unit/milliliter: negative 7-10 Unit/milliliter: weak positive Higher then 10 Unit/milliliter: positive
Time frame: Base line
Periodontal pocket depth and clinical attachment level
Lower then 4 millimeter: normal Higher then 4 millimeter: diseased/previously diseased
Time frame: Baseline
Serum level of tumor necrotic factor alpha
Recorded in picogram per milliliter
Time frame: Baseline
Serum level of anti-mutated citrullinated vimentin
Recorded in Unit per milliliter
Time frame: Baseline
Serum level of interleukin 6
Recorded in picogram per milliliter
Time frame: Baseline
Serum level of interleukin 17
Recorded in picogram per milliliter
Time frame: Baseline
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.