Rivaroxaban in Endovenous Laser Ablation With and Without Miniphlebectomy

University Hospital, Basel, Switzerland400 enrolled

Overview

The purpose of this study is to determine retrospectively if the application of rivaroxaban after endovenous laser ablation with and without miniphlebectomy is safe and if it lowers the risk of venous thrombosis.

Rivaroxaban is an orally active direct factor Xa inhibitor, that is used for thrombosis prophylaxis for example in the setting of orthopaedic surgery. In the observed situation Rivaroxaban was applied in a dosage of 10mg daily during 5 days after endovenous laser ablation.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Varicose Veins Venous Thrombosis Thromboembolism Bleeding

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients age greater than 18 years, informed consent was given. * Endovenous Laser Ablation (EVLA) of the greater saphenous vein (GSV), autologous saphenous vein (ASV) and/or small saphenous vein (SSV) using 1470 nm wavelength radial laser (ELVeS, Biolitec, Austria) and postinterventional Endothermal Heat Induced Thrombosis (EHIT) prophylaxis with rivaroxaban. Exclusion Criteria: Patients are ineligible if they had: * an endovenous ablation technique other than EVLA, * other veins than GSV, ASV or SSV treated with EVLA (i.e. perforators), * postinterventional EHIT prophylaxis other than prophylactic dose of rivaroxaban or * informed consent was not given.

Locations (1)

University Hospital Basel

Basel, Canton of Basel-City, Switzerland

Outcomes

Primary Outcomes

Number of patients with a EHIT class 3 or class 4 within 6 weeks after endovenous laser ablation

Time frame: within 6 weeks after endovenous laser ablation

Secondary Outcomes

Number of major or clinically relevant bleedings within 6 weeks after endovenous laser ablation.

Time frame: within 6 weeks after endovenous laser ablation

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.