In this clinical trial, the investigator will clarify the difference in pharmacokinetics between the group single dose Cavir Tab. 0.5mg and single dose Cavir Tab. 0.5mg with high fatty meal for healthy adult volunteer. The investigators evaluate the effect of food intake on the absorption of Cavir Tab. 0.5mg.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
30
After drug administration, Blood sampling for Pharmacokinetics (Entecavir concentration)
After drug administration, Blood sampling for Pharmacokinetics (Entecavir concentration)
After drug administration, Blood sampling for Pharmacokinetics (Entecavir concentration)
Peak plasma concentration (Cmax) of Entecavir.
phamacokinetic parameter
Time frame: Within 6 Months After Final Visit of Subject
Area under the plasma concentration versus time curve, last (AUClast) of entecavir.
phamacokinetic parameter
Time frame: Within 6 Months After Final Visit of Subject.
Number of participants with adverse events.
Time frame: Within 6 Months After Final Visit of Subject
Area under the plasma concentration versus time curve, infinite (AUCinf) of entecavir.
Pharmacokinetic parameter
Time frame: Within 6 Months After Final Visit of Subject.
The time at which the Cmax is observed (Tmax) of entecavir.
Pharmacokinetic parameter, Cmax is the peak plasma concentration.
Time frame: Within 6 Months After Final Visit of Subject.
Terminal half-life (T1/2) of entecavir.
Pharmacokinetic parameter
Time frame: Within 6 Months After Final Visit of Subject.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.