Anti-recurrence Treatment of Postresection on HCC Patients With MVI Presence and Over-expression of ASPH

Inclusion Criteria: 1. Via clinical diagnosis and confirm it is primary liver cancer 2. Pathological evidence of HCC 3. Confirm presence of MVI and over-expression of ASPH after opreation 4. Within Milan criteria 5. Estimate tumor can gain treatment of curing operation 6. No evidence for extrahepatic metestasis 7. liver function ：Child-Pugh A/B Exclusion Criteria: 1. Reject to attend 2. Impossible to come to our hospital for physical examination regularly 3. Patients with apparent cardiac, pulmonary, cerebral and renal dysfunction 4. Female with pregnancy or during the lactation period