Upper Airway Collapse in Patients With Obstructive Sleep Apnea Syndrome by Drug Induced Sleep Endoscopy

Technical University of Munich43 enrolled

Overview

This is a prospective, interventional cohort study of drug-induced sleep endoscopy (DISE). The goal is to evaluate the upper airway in a cohort of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) diagnosed in a prior polysomnography. This study correlates the sedation level measured by entropy during DISE using propofol via a TCI pump with the local obstruction patterns of the upper airway according to the VOTE classification. As OSAHS is a widespread disease and the DISE procedure has become a common tool for diagnosis and evaluation of further treatment, a growing number of research articles deal with this topic. These articles are available through pubmed.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Sleep Apnea Syndrome

Interventions

Titration of propofol using a target controlled Infusion pump and description of the upper airway according to the VOTE classification

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * documented sleep apnea Syndrome with an AHI \> 5 diagnosed by polysomnography Exclusion Criteria: * active infection * performed oral, head or neck surgery, pregnancy, * ASA classification III or higher, * chronic use of alcohol, sedatives or illicit drugs and chronic * obstructive pulmonary disease.

Locations (1)

Klinik für Anaesthesiologie

Munich, Bavaria, Germany

Outcomes

Primary Outcomes

collapse of the upper airway according to the VOTE classification

Time frame: 30 minutes

Data from ClinicalTrials.gov

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