Enteral Nutrition and Amino Acid Absorption

N/ACompletedNCT02590120

Société des Produits Nestlé (SPN)6 enrolled

Overview

The purpose of this study is to evaluate amino acid absorption with two different type of proteins.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Malabsorption

Interventions

Enteral nutritionDIETARY_SUPPLEMENT

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with gastrointestinal disorder : citrulline plasma concentration \< 20 µmol/L and/or xylose plasma concentration \< 1,7 mmol/L * Patient under enteral nutrition at home * Patient already receiving 1 L by day Exclusion Criteria: * Obese patient BMI \> 30 * Diabetes * Renal or liver failure * Glucocorticoids treatment

Locations (1)

CHU de Lille

Lille, France

Outcomes

Primary Outcomes

Amino acid absorption profile

Area under the curve of amino acid plasma concentration

Time frame: 48 hours

Secondary Outcomes

Tolerance

Description and occurence of adverse events

Time frame: 48 hours

Nutritional status

Retinol Binding Protein and Transthyretin dosage

Time frame: 48 hours

Essentials amino acid absorption

Area under the curve of plasma concentration

Time frame: 48 hours

Insulinemia evolution

Insulinemia dosage

Time frame: 48 hours

Link between amino acid and insuline

Correlation coefficient

Time frame: 48 hours

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.