Nutrition, Physical Activity, and Cognition in Breast Cancer Survivors

Texas State University, San Marcos68 enrolled

Overview

The purpose of this study is to examine the relationship between nutrition, physical activity and brain function in breast cancer survivors.

The current study will examine the potential relationships between physical activity, dietary intake, body composition and cognition in breast cancer cancer survivors and age-matched women without a previous cancer diagnosis. Additionally, we will measure blood inflammatory markers to explore the relationship between lifestyle factors and inflammation. The study involves two, 1hr appointments at Texas State University. The first visit will include cognitive testing and body composition assessment. Participants will be given an activity monitor to wear for one week and a packet of questionnaires to complete at home. At the second visit, a fasted blood sample will be collected, and participants will complete a food frequency questionnaire.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Breast Cancer Cognitive Impairment Cognition

Interventions

no interventionOTHER

Eligibility

Sex: FEMALEMin age: 30 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Breast cancer survivors must have completed primary treatment (chemotherapy, radiation therapy or both) within past 60 months * age-matched controls must have no previous cancer diagnosis * Female * no history of stroke, heart attack or transient ischemic attack * not currently pregnant; can speak, read, and write English * can attend all testing sessions * not blind or legally blind; nonsmoker * no current use of computer-based brain training games (e.g. Lumosity ®, BrainHQ ®). Exclusion Criteria: * male * \< 30 or \> 70 years of age * breast cancer survivor \> 60 months from last treatment or currently undergoing primary treatment * breast cancer survivor never treated with chemotherapy and/or radiation * previous cancer diagnosis other than breast cancer

Locations (1)

Texas State University

San Marcos, Texas, United States

Outcomes

Primary Outcomes

Cognition

A series of computer-based cognitive tasks will be administered via the NIH Toolbox Cognition Battery

Time frame: Baseline

Secondary Outcomes

Physical Activity

Physical activity will be measured by a waist-worn accelerometer

Time frame: Baseline

Diet Quality

Diet will be assessed by completion of the online-administered 2005 Block Food Frequency Questionnaire

Time frame: Baseline

Body Composition (objectively measured)

Body composition will be evaluated by BOD POD assessment

Time frame: Baseline

Inflammatory Markers

A fasted blood sample will be collected for measurement of inflammatory markers

Time frame: Baseline

Data from ClinicalTrials.gov

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