Nimotuzumab in Combination With Radiotherapy for Esophageal Cancer

Inclusion Criteria: 1. pathologically or cytology diagnosed phase II-III esophageal carcinoma or IV thoracic segments carcinoma with the supraclavicular lymph nodes metastasis. 2. with the measureable lesion of the newly diagnosed the esophageal carcinoma. 3. age 18-75 years old 4. ECOG≤2 5. Expect survival date ≥3 months 6. without serious diseases of important organs 7. signature in the inform consent. Exclusion Criteria: 1. pregnant or breast-feeding women or using a prohibited contraceptive method. 2. with psychiatric diseases. 3. with serious diseases or uncontrolled infection. 4. with history of other tumors. 5. participation other clinical trials within 1 month prior to inclusion in the trial. 6. not the first antitumor treatment .