Hair Fall in Patients on Low Dose Methotrexate

Inclusion Criteria: For Cases * Subjects should be above 18 years of age. * Diagnosed with rheumatoid arthritis and fulfilling the ACR EULAR 2010 criteria. * Should be initiated on methotrexate * Willing to follow up For Controls -Subjects should be above 18 years of age. Exclusion Criteria: For Cases * Subjects with prior exposure to methotrexate in the last 6 months * Subjects suffering from Thyroid (hypothyroidism) * Subjects on leflunomide, or having received leflunomide in the last 6 months * Subjects currently on cyclophosphamide or having received cyclophosphamide in the last 3 months. * Subjects on psychiatric treatment or depression illness. * Subjects who have overlap with other rheumatological disorders which can cause hair fall. * Subjects in 1-5 months of post-partum or post-natal period. * Subjects with female pattern baldness * Subjects with androgenetic alopecia * Subjects with alopecia aereta * Subjects with other scalp conditions which can predispose to hair fall For Controls * Subjects having any family history of alopecia. * Subjects suffering from thyroid. * Subjects having any history of anemia. * Subjects under 1-5 months of post-partum or post-natal period. * Subjects on medications which can cause hair fall. * Subjects on methotrexate for other reasons. * Subjects with female pattern baldness * Subjects with androgenetic alopecia * Subjects with alopecia aereta * Subjects with other scalp conditions which can predispose to hair fall