Brain Electrophysiological Study(EEG/ERP) on Opiate Addicts Treating by Bilateral NAc/ALIC Deep Brain Stimulation

Inclusion Criteria: 1. Age between 18 and 65 years of age, male or female； 2. Opiate addictive over 3 years； 3. Physical detoxification completed（keep abstinent for at least 7 days，acute abstinent syndrome disappeared，morphine urinalysis and naloxone test showed negative)； 4. No obvious neuropsychiatry and personality disorders； 5. No severe infectious disease； 6. Good compliance and be able to complete follow up； 7. General health is good，no severe liver、kidney、heart and lung disease； 8. Informed consent issued Exclusion Criteria: 1. Severe cognitive disorders（MMSE scale: illiteracy≤17，primary school≤20，secondary school or above≤24）,bad compliance because of dementia,unable to issue the informed content； 2. History of severe neuropsychiatric disease； 3. Epilepsy； 4. severe liver、kidney、heart and lung disease, severe hypertension and severe orthostatic hypotension； 5. Malignant tumor；History of brain trauma；Pregnant female； 6. Patients are taking part in other clinical trials in recent 3 months； 7. Being deem as unfit for the trials by researcher.