The Effect of Phosphorus on Diet Induced Thermogenesis

Lebanese American University23 enrolled

Overview

The aim of the trial is to investigate the effect of ingestion of 75g of glucose (with or without phosphorus) on diet induced thermogenesis (using indirect calorimetry) and appetite (using visual analogue scales) in lean and obese healthy subjects

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

TRIPLE

Enrollment

Conditions

Imbalance of Constituents of Food Intake Healthy

Interventions

PhosphorusDIETARY_SUPPLEMENT

PlaceboDIETARY_SUPPLEMENT

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy * Sedentary lifestyle * Stable weight for the past 3 months * On a balanced diet Exclusion Criteria: * Underweight (BMI\<18.5) or overweight/obese (BMI≥25) * age \<18 or \> 30 years * Inability to give valid consent * Presence of a chronic or acute illness. * Elevated physical activity level (assesses by the physical activity questionnaire) * Heavy smokers (≥1 pack per day). * Weight gain or loss of \> 3% in the past 3 months * History of kidney stones

Outcomes

Primary Outcomes

Diet Induced Thermogenesis

Diet Induced Thermogenesis will be measured using indirect calorimetry (VO2 consumption)

Time frame: 180 minutes (measured every 30 min)

Data from ClinicalTrials.gov

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