Examination of Potassium Levels in Saliva in ESRD Patients

Hadassah Medical Organization50 enrolled

Overview

Dialysis patients typically undergo 3 treatments a week every other day with an almost 3 day gap during the weekend. After this gap and before the first dialysis of the week the serum Potassium level is expected to be maximal. Participants will be recruited from the dialysis clinic at Hadassah Ein Kerem Hospital. The research team would personally meet the patients who answer inclusion criteria f and ask whether they wish to participate. Each willing participant will undergo Sialometry and blood will be drawn from the dialysis connections for CBC and Biochemistry to establish a baseline. The study measurements namely Sialometry and collection of Saliva as well as blood test will be taken before the initiation of the dialysis. Blood testing will be done via the laboratories of the Hadassah hospital. Saliva analysis will be done in the research lab of Prof. Doron Aframian.

Study Type

OBSERVATIONAL

Enrollment

Conditions

ESRD

Interventions

sialometryPROCEDURE

potassium evaluation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Present a predialysis serum potassium level over 5 mmol/L. Exclusion Criteria: * Pregnancy Patients diagnosed with a pathology of the salivary glands such as Sjogren's syndrome, Sialosis, Sialadenitis. Patients who have received previous radiation therapy to the head and neck region

Outcomes

Primary Outcomes

potassium level in saliva

Time frame: 7 days

Standard Biochemistry of blood