Measurements of Structured Light Plethysmography (SLP) using a chest wall movement based method will be compared to those obtained by spirometry using a flow based pneumotachograph method. This study will enable validation of SLP in children and adults by allowing direct comparison of simultaneous measurements of breathing sequences using the two measurement techniques. The investigators will also examine, in a group of normal adults, repeatability of the agreement between the two devices, and whether the agreement is affected by a change in tidal breathing parameters.
Measurements using the Structured Light Plethysmography method will be compared to those obtained by spirometry using a flow based pneumotachograph. Spirometry is the gold standard for measuring lung function in both clinical support and research roles. Modern spirometers are high precision, reliable instruments enabling a large numbers of parameters relating to lung volumes and the rate of emptying the lungs during a forced expiration to be measured. The most common and accurate method to measure the patient's forced expiration is via pneumotachograph which measures the flow of air through a mouthpiece and integrates the signal to derive the volume expired. Structured Light Plethysmography (SLP) system that measures changes of the chest and abdominal wall movement during breathing by modelling the thorax and abdominal surface defined by a projected structured light pattern which enables a grid of virtual parts to be formed, the movement of which is recorded by digital cameras. SLP provides non-contact assessment to provide lung function data utilising structured light technologies and enhanced imaging processing. In this study direct comparison will be made of measurements recorded simultaneously using the two measuring devices in children and adults. To examine repeatability of the agreement between tidal breathing parameters measured by two techniques, repeated measurements will be performed in each of a group of normal adult subjects. The investigators will also examine whether the agreement is affected by a change in tidal breathing parameters. To obtain a change in tidal breathing parameters, measurements will be recorded during resting spontaneous breathing and after a period of exercise to elevate Respiratory Rate.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
41
Non contact device that uses light to record displacement of the anterior thorax and abdomen region
Device that measures airflow at the mouth using a mouthpiece
Cambridge University Hospitals Foundation Trust
Cambridge, Cambridgeshire, United Kingdom
Forced Vital Capacity (FVC) measured in Litres
The volume of air a person can exhale during a maximal forced breath
Time frame: 5 minutes
Forced Expiratory Volume in one second (FEV1) measured in litres per second
The volume of air a person can exhale in one second during a maximal forced breath
Time frame: 5 minutes
Peak Expiratory Flow (PEF) measured in litres per second
The maximal flow a person can achieve during a maximal forced breath
Time frame: 5 minutes
Respiratory Waveform
Visual comparison of respiratory waveform shape and amplitude produced by pneumotachograph and SLP.
Time frame: 5 minutes
Respiratory Rate (RR) measured in seconds
Tmings derived from the Respiratory Waveforms
Time frame: 5 minutes
Inspiratory Time (tI) measured in seconds
Timings derived from the Respiratory Waveforms
Time frame: 5 minutes
Expiratory Time (tE) measured in seconds
Timings derived from the Respiratory Waveforms
Time frame: 5 minutes
Total breath time (tTot) measured in seconds
Timings derived from the Respiratory Waveforms
Time frame: 5 minutes
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Inspiratory/expiratory ratio (tI/tE) expressed as a ratio
Timing ratios derived from the Respiratory Waveforms
Time frame: 5 minutes
The duty cycle (tI/tTot) expressed as a ratio
Timing ratios derived from the Respiratory Waveforms
Time frame: 5 minutes