Open-Label Study of OTO-201 in Pediatric Subjects With a History of Otitis Media Requiring Tympanostomy Tubes

Inclusion Criteria includes, but is not limited to: * Subject is a male or female aged 6 months to 17 years, inclusive * Subject has a history of otitis media requiring bilateral tympanostomy tube placement * Subject's caregiver is willing to comply with the protocol and attend all study visits Exclusion Criteria includes, but is not limited to: * Subject has a history of prior ear or mastoid surgery, not including myringotomy or myringotomy with TT placement * Subject has been designated for any other surgical procedure that would occur concurrently with TT placement, except adenoidectomy, airway endoscopy, nasal endoscopy, and nasal cautery for epistaxis * Subject has a history of sensorineural hearing loss