The central aim of this study is to test the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE), an intervention designed to disrupt the risk chain leading from chronic pain to prescription opioid misuse and addiction. The investigators plan to conduct a full scale clinical trial to determine whether MORE (relative to a support group control condition) can reduce symptoms of chronic pain and opioid misuse among patients who are receiving pain management in primary care via long-term opioid analgesic therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
250
Mindfulness-Oriented Recovery Enhancement (MORE) is a group behavioral intervention that unites mindfulness training, cognitive reappraisal, and positive psychological principles into an integrative intervention strategy targeting mechanisms of pain and opioid misuse.
A conventional support group will allow participants to express emotions, share experiences, and receive social support under the guidance of a skilled therapist.
University of Utah Primary Care Clinics
Salt Lake City, Utah, United States
Change in opioid misuse
Opioid misuse as evidenced by triangulated aggregate of Current Opioid Misuse Measure and/or clinician assessment via Addiction Behaviors Checklist and/or urine screen
Time frame: Change from baseline through study completion (9 months post-treatment)
Change in pain severity and interference
Brief Pain Inventory
Time frame: Change from baseline through study completion (9 months post-treatment)
Change in opioid craving
Opioid craving measure from Wasan et al. 2012
Time frame: Change from baseline through study completion (9 months post-treatment)
Change in psychological distress
Depression Anxiety Stress Scale
Time frame: Change from baseline through study completion (9 months post-treatment)
Change in opioid dose
Opioid dose converted into morphine equivalents via standardized equianalgesic tables
Time frame: Change from baseline through study completion (9 months post-treatment)
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