Assessment of Persistent Cognitive Impairment After Cure of Cushing's Disease

Inclusion Criteria: Patients : * history of Cushing's Disease * aged : 18 - 60 years * Biological remission of Cushing's disease for at least one year * Affiliation to Social Security * Informed consent signed by patient and investigator (at the latest the inclusion's day, before study's exams) For controls : * People aged 18 to 60 years matched to patients for age, sex and educational level * Affiliation to Social Security * Informed consent signed by patient and investigator (at the latest the inclusion's day, before study's exams) Exclusion Criteria: For patients : * Persistent hypercortisolism (even mild) * Current treatment of hypercortisolism with drugs * Obesity (BMI \>30 kg/m²) * Alcohol or drug addiction present or past * Growth hormone deficit * Diabetes mellitus with hemoglobin A1c \> 7.5% and/or fasting blood glucose \> 1.4 g/L * History of pituitary radiotherapy * History of cerebrovascular or neuro-cerebral disease * untreated dysthyroidism * Current psychotropic drug treatment * Pregnancy * Use of glucocorticoids in the last 3 months before study (aside hydrocortisone replacement therapy) * Excessive hydrocortisone replacement therapy (unadjusted to weight and/or with evening administration) For controls : * Obesity (BMI \>30 kg/m²) * Alcohol or drug addiction present or past * Current psychotropic drug treatment * History of cerebrovascular or neuro-cerebral disease * Current pregnancy * Chronical use of corticoid (\> 1 month), current or past * Use of glucocorticoids in the last 3 months before study (aside hydrocortisone replacement therapy) * Diabetes mellitus with hemoglobin A1c \> 7.5% and/or fasting blood glucose \> 1.4 g/L * Obesity (BMI \>30 kg/m²) * untreated dysthyroidism