Paralympians competing in wheelchair sports may experience a very high glycolytic demand (and therefore acidotic environment) in their upper-body muscles, particularly in high-intensity disciplines. Previous studies from our group have shown that upper-body exercise is very sensitive to the ergogenic effects of β-alanine supplementation and to other nutritional supplements capable of increasing buffering capacity. In line with this, have shown that upper-body muscle groups benefit more from artificially induced alkalosis than lower-body muscle groups. Although β-alanine appears to be an interesting and potential ergogenic supplement for paralympians, no study to date has assessed its potential in wheelchair athletes.In this study, we will evaluate the effects of β-alanine supplementation on upper-body performance in wheelchair athletes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
TRIPLE
Enrollment
20
School of Physical Education and Sports, University of Sao Paulo
São Paulo, São Paulo, Brazil
Exercise performance (Time to exhaustion test)
Time to exhaustion test performed on arm crank ergometer
Time frame: 28 days
Muscle carnosine content before and after supplementation
Assessed by muscle biopsy samples before performance tests
Time frame: 28 days
Muscle carnosine content in trained (deltoid) vs. untrained (vastus lateralis) muscles
Deltoids microbiopsy and vastus lateralis biopsy
Time frame: 28 days
Blood pH.
1 mL venous blood sample
Time frame: 5 minutes after performance tests
Safety of beta-alanine supplementation measured by complete hemogram analysis
Time frame: 28 days
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