The study intends to measure fibrinogen plasma levels during the first 24 hrs in cardiac and thoracic surgical patients who undergo surgical procedures using extracorporeal circulation.
Study Type
OBSERVATIONAL
Enrollment
26
At 12 different time points investigators plan to measure the plasma fibrinogen level with conventional coagulation tests (Clauss fibrinogen) and with ROTEM.
University Hospital Bern
Bern, Switzerland
Plasma fibrinogen concentration
Conventional (Clauss) and thromboelastometric measurement (FIBTEM)
Time frame: through study completion, an average of 1 year
Periprocedural thromboembolic complications
Time frame: through study completion, an average of 1 year
Thoracic drain loss
Measurement of the amount of blood collected by the thoracic drain (ml)
Time frame: through study completion, an average of 1 year
In-hospital mortality
Time frame: through study completion, an average of 1 year
Intensive Care Unit (ICU) length of stay
Time frame: through study completion, an average of 1 year
Platelet count
Measurement of platelet count in the laboratory
Time frame: through study completion, an average of 1 year
Prothrombin time (Quick)
Measurement of Quick in the laboratory
Time frame: through study completion, an average of 1 year
Activated partial thromboplastin time (aPTT)
Measurement of aPTT in the laboratory
Time frame: through study completion, an average of 1 year
Thromboelastometric (ROTEM) parameters (e.g., INTEM, EXTEM, HEPTEM)
Measurement of ROTEM parameter (unit mm) in the laboratory
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Time frame: through study completion, an average of 1 year
Thrombin concentration
Thrombin concentration in the plasma as measured in the laboratory
Time frame: through study completion, an average of 1 year