Primary Objective: -To assess the change in glycosylated hemoglobin (HbA1c) in uncontrolled Type 2 diabetes patients on OAD agent in Jordan after 6 months of treatment with basal insulin (Insulin glargine). Secondary Objectives: * To evaluate the percentage of patients achieving target of HbA1c ˂7%. * To evaluate the change in fasting plasma glucose (FPG). * To assess the following safety criteria: hypoglycemic events, body weight changes, and overall safety. * Describe the titration process: changes in glargine insulin dose at 3 months and 6 months, changes in the titration doses used (if any), and time to reach control.
The total duration of study period per patient is up to 6 months.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
242
Pharmaceutical form:Solution Route of administration: Subcutaneous
JORDAN
Jordan, Jordan
Change from baseline in HbA1c
Time frame: Baseline, 6 months
- Percentage of patients achieving target of HbA1c <7%
Time frame: 6 months
- Change from baseline in fasting plasma glucose values
Time frame: Baseline, 3 months, and 6 months
- Percentage of patients with hypoglycemic events
Time frame: Baseline, 6 months
- Change from baseline in body weight
Time frame: Baseline, 3 months and 6 months
- Number of patients with adverse events
Time frame: Baseline, 6 months
- Change in dose of insulin glargine
Time frame: 3 months and 6 months
- Change in the titration doses used (if any)
Time frame: 6 months
- Time to reach control
Time frame: 6 months
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