Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer.

Inclusion Criteria: * Pathologically or cytologically confirmed esophageal squamous cell carcinoma. * Stage II-IVa ESCC confirmed by endoscopic ultrasonography(EUS) and imaging studies. * Aging from 70 to 80. * Eastern Cooperative Oncology Group (ECOG) performance status 0-2. * Charlson's weighted index of comorbidities (WIC) ≤4； * White blood cell count ≥4×109 /L, neutrophile granulocyte count≥1.5×109 /L, platelet count≥100×109 /L, hemoglobin ≥100 g /L, serum creatinine and bilirubin 1.5 times less than the upper limits of normal (ULN),aminotransferase two times less than the ULN. * Weight loss ≤15% within the past half year. * Forced expiratory volume in 1 s≥ 1 L. * Patients and their family signed the informed consents. Exclusion Criteria: * Previous or recent another malignancy, except for nonmelanoma skin cancer or cervical cancer in situ. * Already received antineoplastic therapy,including chemotherapy, radiotherapy or operation. * Any contraindication for chemotherapy or radiotherapy(such as a myocardial infarction within 6 months,immunosuppressive therapy,symptomatic heart disease,including unstable angina pectoris, congestive heart failure,and uncontrolled arrhythmia.) * Malignant pleural effusion or pericardial effusion. * Weight loss \>10% within the past 3 months. * Recruited in other clinical trials within 30 days * Drug addiction, long-term alcohol abuse and AIDS patients. * Uncontrollable epileptic attack or psychotic patients without self-control ability. * Severe allergy or idiosyncrasy. * Not suitable for this study judged by researchers.