Subjects who received tesevatinib in Study KD019-101 and completed 24 months of treatment will continue on the dose of tesevatinib they were receiving at 24 months on the KD019-101 study.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
15
UCLA Medical Center
Los Angeles, California, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Washington University School of Medicine
St Louis, Missouri, United States
Cleveland Clinic
Cleveland, Ohio, United States
Monitor Longitudinal Changes in Estimated Glomerular Filtration Rate
Monitor longitudinal changes in estimated glomerular filtration rate (eGFR) in subjects with ADPKD when treated with tesevatinib.
Time frame: 37 Months
Monitor Longitudinal Changes in Total Kidney Volume
Monitor longitudinal changes from baseline in total kidney volume (TKV) in subjects with ADPKD when treated with tesevatinib.
Time frame: 37 Months
Number of Subjects Experiencing Adverse Events as a Measure of Safety and Tolerability
To evaluate the long term safety and tolerability of tesevatinib in subjects with ADPKD when treated with tesevatinib.
Time frame: 37 Months
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University of Virginia - Nephrology Clinical Research Center
Charlottesville, Virginia, United States
Medical College of Wisconsin
Milwaukee, Wisconsin, United States