The purpose of the study is to evaluate a 2-3 day treatment probe targeted to improving social gaze behavior in children with fragile X syndrome (FXS). The investigators will use the principles of Applied Behavior Analysis (ABA) to shape appropriate social skills. Importantly, the investigators propose to examine the effects of this treatment probe on brain and behavior.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
71
Appropriate social gaze behavior will be shaped using the principles of Applied Behavior Analysis.
Stanford University School of Medicine
Stanford, California, United States
Percentage of social gaze aversion recorded during the social challenge
Time frame: 3 days
Heart rate recorded during the social challenge
Time frame: 3 days
Total t-score on the Social Responsiveness Scale (SRS)
Time frame: 4 weeks
Verbal responses and pauses in conversation observed during the social challenge
Time frame: 3 days
Fractional Amplitude of Low Frequency fluctuations (fALLF) measured in the insular cortex
Time frame: 3 days
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